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Stem Cell Therapy For Musculoskeletal Disease

Next Generation Stem Cell Therapy for Musculoskeletal Disease

Musculoskeletal disorders affect millions of people worldwide, whether due to injury, aging, or a chronic condition. The regeneration process in musculoskeletal tissues (muscles, tendons, bones) can be affected by various factors, especially excessive inflammation and a decrease in regenerative capacity within intra-articular structures (cartilage, menisci, and ligaments). For many orthopedic conditions, effective non-surgical treatment options are limited. This is where stem cells come into play.

Tissue regeneration requires the recruitment of stem cells to the target site to form tissue-specific cells, as well as new vessels to provide the necessary oxygen, nutrients, and growth factors to repair the affected area.

1. Bone: Stem cell therapy along with exosomes promotes bone healing after an injury by accelerating bone repair through increased cell proliferation and the creation of blood vessels.
 
2. Cartilage: Mesenchymal stem cells have demonstrated their ability to repair cartilage tissue due to their anti-inflammatory effects and reduction of oxidative stress.
 
3. Joints: Joint injury induces the production of proteins that can degrade cartilage and bone. While this proinflammatory response is necessary to initiate the repair process, if not properly controlled, it can contribute to perpetuating chronic inflammation and tissue damage, leading to post-traumatic osteoarthritis. Stem cells have a significant immunoregulatory effect, helping reduce inflammation and pain.
 
4. Muscles, ligaments, and tendons: Mesenchymal stem cells assist in the treatment of disorders and injuries in these tissues due to their capacity to differentiate into functional skeletal muscle cells after acute damage, and their anti-inflammatory capacity helps improve the function of ligaments and tendons.

The cost of the treatment.

The cost is determined based on the dosage and protocol recommended by the doctor, and this is done through a free virtual medical consultation.

Duration of your visit.

The treatment has an approximate duration of 2 to 3 hours, depending on the medical assessment. Some patients may receive their treatment divided into two or more days.

Ground transportation support

We provide transportation from the hotel to the clinic. In the clinics located in Nuevo Laredo, Ciudad Juárez, and Ensenada, transportation is offered from your hotel in the United States to the clinic. In the clinics in Monterrey, Guadalajara, Cabo, and Los Algodones, we offer transfers from the airport to your hotel and on the day of treatment to the clinic. In Cancún, transportation is only provided from your hotel to the clinic on the day of treatment.

Referecences

Malekpour K, Hazrati A, Zahar M, Markov A, Zekiy AO, Navashenaq JG, Roshangar L, Ahmadi M. The Potential Use of Mesenchymal Stem Cells and Their Derived Exosomes for Orthopedic Diseases Treatment. Stem Cell Rev Rep. 2022 Mar;18(3):933-951. doi: 10.1007/s12015-021-10185-z. Epub 2021 Jun 24. PMID: 34169411; PMCID: PMC8224994.

Kangari P, Talaei-Khozani T, Razeghian-Jahromi I, Razmkhah M. Mesenchymal stem cells: amazing remedies for bone and cartilage defects. Stem Cell Res Ther. 2020 Nov 23;11(1):492. doi: 10.1186/s13287-020-02001-1. PMID: 33225992; PMCID: PMC7681994.

Jiang L, Lu J, Chen Y, Lyu K, Long L, Wang X, Liu T, Li S. Mesenchymal stem cells: An efficient cell therapy for tendon repair (Review). Int J Mol Med. 2023 Aug;52(2):70. doi: 10.3892/ijmm.2023.5273. Epub 2023 Jun 30. PMID: 37387410; PMCID: PMC10373123.

Paschos NK, Sennett ML. Update on mesenchymal stem cell therapies for cartilage disorders. World J Orthop. 2017 Dec 18;8(12):853-860. doi: 10.5312/wjo.v8.i12.853. PMID: 29312843; PMCID: PMC5745427.

Wayne Yuk-wai Lee, Bin Wang, Cartilage repair by mesenchymal stem cells: Clinical trial update and perspectives, Journal of Orthopaedic Translation, Volume 9, 2017, Pages 76-88, ISSN 2214-031X, https://doi.org/10.1016/j.jot.2017.03.005.

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