During the aging process, our stem cell numbers decline, and functionality of the stem cells reduces. This decline is increased with disease and injury as more stem cells are forced into use.
There is increasing evidence that the aging process can have adverse effects on stem cells. As stem cells age, their renewal ability deteriorates and their ability to differentiate into the various cell types is altered. Accordingly, it is suggested aging-induced deterioration of stem cell functions may play a key role in the pathophysiology of the various aging-associated disorders.
Understanding the role of the aging process in deterioration of stem cell function is crucial, not only in understanding the pathophysiology of aging-associated disorders but also in the future development of effective stem cell-based therapies to treat aging-associated diseases.
Adult stem cells, also known as somatic stem cells, are found throughout the body in every tissues and organ after development and function as self-renewing cell pools to replenish dying cells and regenerate damaged tissues throughout life.
However, adult stem cells appear to age with the person. As stem cells age, their functional ability also deteriorates. Specifically, this regenerative power appears to decline with age, as injuries in older individuals heal more slowly than in childhood. For example, healing of a fractured bone takes much longer time in elderly than in young individuals.
There is a substantial amount of evidence showing that the deterioration of adult stem cells in the adult phase can become an important player in the initiation of several diseases in aging.
At Trinity Stem Cell Treatment Center, our stem cells are used to treat a wide range of chronic diseases and for rejuvenating affects for ageing.
We believe keeping the mesenchymal stem cells juvenile and functioning in a youthful manner, will deliver the most beneficial regenerative medicine treatment.
Aging is characterized by common environmental conditions, such as hormonal, immunologic, and metabolic disorders and these are considered as the critical microenvironmental factors affecting stem cell functions.
In mammals, spontaneous and extrinsic mutational events occur on DNA on a daily basis. While most of the damaged DNAs are repaired by normal DNA repair mechanism, some of the mutated DNAs appear to escape from the repair mechanism and accumulate over time.
Mitochondria are ubiquitous intracellular organelles in mammals and are the main source of cellular adenosine triphosphate (ATP) that plays a central role in a variety of cellular processes.
Epigenetics refers to changes in gene expression, which are heritable through modifications without affecting the DNA sequence. It has also been defined more broadly as the dynamic regulation of gene expression by sequence-independent mechanisms, including but not limited to changes in DNA methylation and histone modifications.
Trinity Stem Cell Clinic Nuevo Laredo
Hospital Mexico Americano
Suite 215 Esteban Baca Calderón 4400
Colonia La Concordia
Nuevo Laredo, Tamaulipas Mexico
CP 88298
Trinity Stem Cell Clinic Juarez, Chihuahua
Poliplaza Diamante Calle de la
labranza 7398 Villas del granjero
C. Juárez - México
Trinity Stem Cell Clinic Ensenada
Velmar Hospital
Ensenada, B.C., Mexico
CONTACTS
info@trinitystemcells.com
PHONE
Trinity Direct Line
+1 (956) 267-1586
Trinity Direct Line
+52 81 33680103
Trinity Stem Cells Clinic Monterrey
AVE Medical Center
64710 Monterrey, N.L., Mexico
Trinity Stem Cells Clinic Guadalajara
Av. Central #911-A, N10-5B y 7B,
Col. Residencial Ponientem
C.P. 45136,
Zapopan, Jalisco
Trinity Stem Cells Clinic Cancún
Hospital Americano Cancún
Suite 211
Retorno, Viento 15,4
Cancún, Quintana Roo, México
CP 77500